Bacterial genome expression


The algorithm (triad pattern) detects strong promoters in bacterial genome expression and provides information on over-expressed genes. In particular, it has been used to identify strong promoters in coryneform bacteria of industrial importance.

Consensus of strong promoters in hyperthermophilic bacterium Thermotoga maritima.

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Representative references:

1. Dekthyar M., Morin A., Sakanyan V. Triad pattern algorithm for predicting strong promoter candidates in bacterial genomes. BMC Bioinformatics 2008, 9, 233, doi; 10.1186/1471-2105-9-233. PDF

2. Koloyan A. O., Hambardzumyan A. A., Hovsepyan A. S., Dekhtyar M. I., Saghiyan A. S., Sakanyan V. A. Virtual screening of coryneform bacteria genome for the presence of strong promoters. Biotechnologiya 2010, 1, 41-50.