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Patents:
We have exclusive rights for World Patent Applications owned by the
University of Nantes.
Publications in the protein micro-array
field:
- 1.
Ghochikyan A., Karaivanova I., Lecocq M., Vusio P., Arnaud M.C., Snapyan M.,
Weigel P., Guevel L., Buckle M., Sakanyan V. Arginine operator binding by
heterologous and chimeric ArgR repressors from E. coliB. stearothermophilus.
J. Bacteriol. 2002, 184:
6602-6614.
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2.
Snapyan M., Lecocq M., Guevel L., Arnaud M.-C., Ghochikyan A., Sakanyan V.
Dissecting DNA-protein and protein-protein interactions involved in bacterial
transcriptional regulation by a sensitive protein array method combining a
near-infrared fluorescence detection. Proteomics
2003, 3: 647-657.
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3.
Morin A., Huysveld N., Braun F., Dimova D., Sakanyan V., Charlier D.
Hyperthermophilic Thermotoga arginine
repressor binding to full-length cognate and heterologous arginine operators
and to half-site targets. J. Mol. Biol. 2003, 332: 537-553.
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4.
Saghatelyan A. K., Snapyan M.,
Gorissen S., Meigel I., Mosbacher J., Kaupmann K., Bettler B., Kornilov
A. V., Nifantiev N. E., Sakanyan V., Schachner M., Dityatev A. Recognition
molecule associated carbohydrate inhibits postsynaptic GABAB
receptors: a mechanism for homeostatic regulation of GABA release in
perisomatic synapses. Mol. Cell.
Neurosci. 2003, 24: 271-282.
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5. Arnaud M.-C., Gazarian T., Palacios Rodriguez
Y., Gazarian K., Sakanyan V. Array assessment of phage displayed peptide mimics
of Human Immunodeficiency Virus type 1 gp41 immunodominant epitope: binding to
antibodies of infected individuals. Proteomics
2004, 4: 1959-1964.
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6. Sakanyan V. Puces à protéines: nouvelle
approche du diagnostic des maladies infectieuses. Antibiotiques 2004, 6: 185-192.
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7.
Sakanyan V. High-throughput and multiplexed protein array technology:
protein-DNA and protein-protein interactions. J. Chromatography B 2005, 815: 77-95.
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8.
Yeretssian G., Lecocq M., Lebon G., Hurst H., Sakanyan V. Competition on
nitrocellulose-immobilized antibody arrays: from bacterial protein binding
assay to protein profiling in breast cancer cells. Mol. Cell. Proteomics 2005, 4: 605-617.
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9.
Braun F., Marhuenda F., Morin A., Guevel L., Fleury F., Takahashi M., Sakanyan
V. Similarity and divergence between the RNA polymerase α subunits
from hyperthermophilic Thermotoga
maritima and mesophilic Escherichia
coli bacteria. Gene 2006, 380:
120-126.
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10.
Sakanyan V., Yeretssian G. Near infrared fluorescence detection of
antigen-antibody interactions on microarrays. In: Spectral Techniques in Proteomics. Ed. D. Sem, CRC Press, 2007, p.
185-205.
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11.
Snapyan M., Sakanyan V. DNA interactions with protein microarrays. In: Functional protein microarrays in drug
discovery. Ed. P. Predki, Taylor & Francis Group, LLC, 2007, p.
309-328.
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12.
Sakanyan V. Protein microarrays and perspectives of their application in
medicine. Laboratory diagnostics in
Russia. Annual reference book (Part
of Thermo Fisher Scientific), 2007, p. 47-50.
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13. Sakanyan V., Arnaud M.-C. Puces à
protéines et les perspectives des applications médicales. ITBM-RBM 2008, 28: 187-193.
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14.
Gaudin J-C., Rabesona H., Choiset Y., Yeretssian G., Chobert J-M., Sakanyan V.,
Drouet M., Haertlé T. Assessment of the IgE-mediated immune response to
milk-specific proteins in allergic patients using microarrays. Clinical and Experimental Allergy 2008,
38: 686-693.
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15.
Dekthyar M., Morin A., Sakanyan V. Triad pattern algorithm for predicting
strong promoter candidates in bacterial genomes. BMC Bioinformatics 2008, 9: 233, doi:10.1186/1471-2105-9-233.
- 16.
Sakanyan V. Molecular interactions on microarrays. Eur. Biopharm. Review
2008, November, 74-78.
- 17.
Feron M., Guevel L., Rouger K., Dubreil l., Arnaud MC, Ledevin M., Megeney LA,
Cherel Y., Sakanyan V. PTEN contributes to profound PI3K/Akt signalling pathway
deregulation in dystrophin-deficient drug muscle. Amer. J. Pathol. 2009,
174: doi: 10.2353/ajpath.2009.080460.
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18. Dupuy
L., Gauthier C., Durand G., Musnier A., Heitzler D., Herledan A.,
Sakanyan V., Crépieux P, Reiter E. A highly sensitive near-infrared
detection method to analyze signalling pathways by reverse-phase
protein array. 2009 (in press).
- 19.
Guedj N., zhan Q., Perigny M., Rauyou PE, Degos F., Belghiti J., Farges
O., Bedossa P., Paradis V., Comparative protein expression profiles of
hilar and peripheral hepatic cholangiocarcinomas. Journal of Hepatology
2009, April.
- 20. Bitoun M., Durieux AC., Prudhon B.,
Bevilacqua J., Herledan A., Sakanyan V., Urtizberea A., Cartier L.,
Romero NB., Guicheney P., Dynamin 2 Mutations Associated With Human
Diseases Impair Clathrin-Mediated Receptor Endocytosis. Human Genome
Variation Societey Official Journal 2009 June.
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