Proteins are major actors involved in many physiological processes. Variation in mRNA expression does not necessarly reflect the protein yield in cells. Therefore, your DNA array data require further confirmation by antibody arrays.

Antibody arrays can evaluate real variations in protein profiling and post-traductional modifications in cells. You have a unique opportunity to assess up- and down-expression of proteins in various biological samples, i.e. in healthy and diseased cells.

Protein samples can be prepared from cells, biopsies and blood. Proteins of your interest can be subextracted from cells in order to assess their expression modulation in different compartments. Bound complexes are detected using dual fluorescent detection (700 nm & 800 nm).

We developped MAGYarray, antibody array directed against cell cycle, cytoskeleton, xenobiotic metabolism.
We also prepare arrays of your particular interest.

Guedj N., zhan Q., Perigny M., Rauyou PE, Degos F., Belghiti J., Farges O., Bedossa P., Paradis V., Comparative protein expression profiles of hilar and peripheral hepatic cholangiocarcinomas. Journal of Hepatology 2009, April.